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3D electron microscopy for analyzing nanoparticles in the tumor endothelium

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Proceedings of the National Academy of Sciences, Volume 121, Issue 51, December 2024.
SignificanceDelivering medical agents (e.g., using nanoparticles) into tumors is necessary for treating cancer. Conventional electron microscopy (EM) can visualize single nanoparticles but is limited to thin two-dimensional (2D) tissue slices. 2D analysis …
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